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tnf superfamily -  1

Publish Date: 30-11-2016 02:27:11 | Contact name: Linna Green | Location: USA | Place: Shirley | 2 times displayed |

Tumor necrosis factor (TNF) superfamily composes of a group of cytokines and their receptors which can reduce cell death (apoptosis). This superfamily is composed of 19 ligands and 29 receptors in humans. TNFα and Lymphotoxin-alpha (LTα) is first identified members of the family.
TNF superfamily is a pro-inflammatory cytokine that was identified over 4 decades ago as the factor induced by lipopolysaccharide (LPS) that causes apoptosis and necrosis (cell death) of several cancer cell lines and the regression of some cancers in experimental animal models.

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Phone: 5166698109




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